Sometimes less is more: Messier nanoparticles may actually deliver drugs more effectively than tightly packed ones

Feb 23, 2026 - 22:16
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Sometimes less is more: Messier nanoparticles may actually deliver drugs more effectively than tightly packed ones
The tiny fatty capsules that deliver COVID-19 mRNA vaccines into billions of arms may work better when they're a little disorganized. That's the surprising finding from researchers who developed a new way to examine these drug-delivery vehicles one particle at a time—revealing that cramming in more medicine doesn't always mean better results.

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